Autism – Symptoms REVERSED in New Study
(NNB) Symptoms of autism were reversed in a study published in April of 2017 by Annals of Clinical and Translational Neurology.1 Five children, average age of 9 years old, received one dose of suramin – a manmade drug first synthesized in 1916. The results were remarkable:
•Improved scores for language
•Improved scores for social interactions
•Decreased restricted or repetitive behaviors
None of the improvements occurred in the placebo group. This was the first study in the published, scientific literature to analyze the effect of suramin in a pediatric population of autistic children. And, it worked! According to the study, after a single dose of suramin, “the rate of language, social, behavioral, and developmental improvements continued to increase for 3 weeks,” but then the symptoms began to re-appear.1
Even though the reversal of symptoms was temporary, the study demonstrates that autism may not be a genetic life-sentence; it may not be permanent.
Autism may be reversible.
It’s theorized that suramin worked by dampening the cell danger response (CDR). When cells perceive a threat that could injure or kill them, the CDR is activated. As a result, inflammation in the body increases as part of a protective mechanism. That protective response is supposed to be temporary; once the threat is removed, the CDR is supposed to be deactivated. However, in children with autism, it’s theorized that the CDR persists even after the threat has been eliminated.1,2
This new study demonstrates that the CDR in autistic children can be turned down and that “normal” metabolism can be restored.1 In other words, symptoms of autism can be reversed, at least to some degree, by lowering inflammation.
The key to reversing autism may be reducing inflammation.
We know that autism is an inflammatory disease.3,4 “It’s the inflammation that compromises brain function in children and even in adults,” according to Dr. Perlmutter, neurologist and author of The Grain Brain.5 In fact, we’re now learning that symptoms of autism, including lack of focus and characteristic behavioral traits, are “manifestations of an underlying inflammatory problem.”5 This new study supports that hypothesis – suramin decreased symptoms of autism, in part, by decreasing inflammation.1
That’s great news because it means that if you lower inflammation, you can reverse the symptoms or – at a minimum – improve quality of life. How do you lower the inflammation?
One approach is to use a drug, like suramin. However, it may work by addressing the symptoms. A different approach is to address the root of the problem: